Systemic inflammatory response syndrome (SIRS) is an exaggerated defense response of the body to a noxious stressor (infection, trauma, surgery, acute inflammation, ischemia or reperfusion, or malignancy to name a few) to localize and then eliminate the endogenous or exogenous source of the insult.¹ When working up someone for sepsis or a suspected sepsis, for … Continue reading Infection — SIRS, Sepsis, and MODS