Avoid Novel Oral Anticoagulants (NOACs) in the following groups of patients: severe liver impairment – Child Pugh C renal impairment – Creatinine Clearance (CrCl) < 30 mL / min Pregnancy (warfarin is also contraindicated) Breastfeeding – warfarin is ok Co-administration with strong enzyme / transporter- inducers: e.g. rifampicin inhibitors: e.g. erythromycin established warfarin treatment with … Continue reading Patients in Whom to Avoid NOACs